Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-1-3
pubmed:abstractText
A highly sensitive molecular-imprinted polymer sensor (MIP sensor) for ultratrace oxytetracycline (OTC) determination was prepared based on the competition reaction between template molecule OTC and glucose oxidase (GOD)-labeled OTC (GOD-OTC). Sensitivity improved dramatically due to the detection of a huge amount of enzyme catalytic production, which was inversely proportional to template molecule concentration. The MIP sensor was characterized by alternating current impedance spectroscopy and cyclic voltammetry, and its voltammetric behavior was also verified. Experimental conditions including isolation, incubation, and competition were optimized. OTC can be determined at concentrations between 0 and 4.0×10(-7) mol/L with a detection limit of 3.30×10(-10) mol/L by the differential pulse voltammetry technique. The MIP sensor showed high sensitivity, selectivity, reproducibility, and good recovery in sample determination.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1873-4235
pubmed:author
pubmed:copyrightInfo
Copyright © 2010. Published by Elsevier B.V.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2097-101
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Fabrication of an oxytetracycline molecular-imprinted sensor based on the competition reaction via a GOD-enzymatic amplifier.
pubmed:affiliation
College of Chemistry and Bioengineering, Guilin University of Technology, Jiangan Road, Guangxi, 541004, China. likianping@263.net
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't