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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-10-19
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pubmed:abstractText |
Abnormalities of 11q23 involving the MLL gene are found in approximately 10% of human leukemias. To date, nearly 100 different chromosome bands have been described in rearrangements involving 11q23 and 64 fusion genes have been cloned and characterized at the molecular level. In this work we present the identification of a novel MLL fusion partner in a pediatric patient with de novo biphenotypic acute leukemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
pubmed-author:BizarroSusanaS,
pubmed-author:CerveiraNunoN,
pubmed-author:CorreiaCecíliaC,
pubmed-author:LisboaSusanaS,
pubmed-author:MarschalekRolfR,
pubmed-author:MeyerClausC,
pubmed-author:NortonLucíliaL,
pubmed-author:PinheiroManuelaM,
pubmed-author:SantosJoanaJ,
pubmed-author:TeixeiraManuel RMR,
pubmed-author:TorresLurdesL
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
518
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pubmed:meshHeading |
pubmed-meshheading:20920256-Antigens, Neoplasm,
pubmed-meshheading:20920256-Child,
pubmed-meshheading:20920256-Chromosome Banding,
pubmed-meshheading:20920256-Chromosomes, Human, Pair 11,
pubmed-meshheading:20920256-Chromosomes, Human, X,
pubmed-meshheading:20920256-Exons,
pubmed-meshheading:20920256-Fatal Outcome,
pubmed-meshheading:20920256-Gene Deletion,
pubmed-meshheading:20920256-Humans,
pubmed-meshheading:20920256-In Situ Hybridization, Fluorescence,
pubmed-meshheading:20920256-Karyotyping,
pubmed-meshheading:20920256-Leukemia, Myeloid, Acute,
pubmed-meshheading:20920256-Male,
pubmed-meshheading:20920256-Myeloid-Lymphoid Leukemia Protein,
pubmed-meshheading:20920256-Oncogene Proteins, Fusion,
pubmed-meshheading:20920256-Open Reading Frames
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pubmed:year |
2010
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pubmed:articleTitle |
A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.
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pubmed:affiliation |
Department of Genetics of the Portuguese Oncology Institute, Porto, Portugal.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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