Linked Life Data

20890810

Source:http://linkedlifedata.com/resource/pubmed/id/20890810

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-3-8
pubmed:abstractText
Three new guaiane-type sesquiterpene lactones (1-3), together with nine related sesquiterpenes (4-12), were isolated from the whole extract of Ixeris dentata (Asteraceae). The chemical structures of isolates 1-12 were established by spectroscopic analyses as 3 ?,8 ?-dihydroxy-guaia-10(14)-en-1 ?,4 ?,5 ?,6 ?,7 ?,11 ?H-12,6 ?-olide (1), ixerin N 6'- O-acetate (2), ixerisoside A 6'- O-acetate (3), ixerin N ( 4), ixerisoside A (5), ixerin M (6), tectroside (7), 8-epidesacylcynaropicrin glucoside (8), 8-epiisolipidiol (9), 11 ?H-11,13-dihydrointegrifolin (10) 8 ?-hydroxy-4 ?,15-dihydrozaluzanin C (11), and integrifolin (12). Compounds 1-12 were evaluated for their inhibitory effect on the proliferation of the cultured human tumor cell lines MES-SA, MES-SA/DX5, HCT-15, and HCT15/CL02 in vitro.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1439-0221
pubmed:author
pubmed:copyrightInfo
© Georg Thieme Verlag KG Stuttgart · New York.
pubmed:issnType
Electronic
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
380-2
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
New guaiane sesquiterpene lactones from Ixeris dentata.
pubmed:affiliation
Korea Research Institute of Chemical Technology, Daejeon, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't