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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0010467,
umls-concept:C0014335,
umls-concept:C0021853,
umls-concept:C0026724,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0173022,
umls-concept:C0287531,
umls-concept:C0542341,
umls-concept:C0599946,
umls-concept:C1333257,
umls-concept:C1366876,
umls-concept:C1705047,
umls-concept:C1833235,
umls-concept:C1879547
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|
pubmed:issue |
9
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pubmed:dateCreated |
2010-10-4
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|
pubmed:abstractText |
Intestinal mucosa barrier (IMB) dysfunction results in many notorious diseases for which there are currently few effective treatments. We studied curcumin's protective effect on IMB and examined its mechanism by using methotrexate (MTX) induced rat enteritis model and lipopolysaccharide (LPS) treated cell death model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:MengFan-SuFS,
pubmed-author:PengDan-danDD,
pubmed-author:SiN VNV,
pubmed-author:SongWei-BingWB,
pubmed-author:WangYuan-YuanYY,
pubmed-author:XiaoBingB,
pubmed-author:XiaoLi-PingLP,
pubmed-author:YuXin-PeiXP,
pubmed-author:ZengJian-YingJY,
pubmed-author:ZhangQing-HuaQH,
pubmed-author:ZhangZhen-ShuZS
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
e12969
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pubmed:meshHeading |
pubmed-meshheading:20885979-Animals,
pubmed-meshheading:20885979-Cell Line,
pubmed-meshheading:20885979-Curcumin,
pubmed-meshheading:20885979-Disease Models, Animal,
pubmed-meshheading:20885979-Dual Specificity Phosphatase 1,
pubmed-meshheading:20885979-Enteritis,
pubmed-meshheading:20885979-Enzyme Activation,
pubmed-meshheading:20885979-Gene Expression Regulation,
pubmed-meshheading:20885979-Humans,
pubmed-meshheading:20885979-Intercellular Adhesion Molecule-1,
pubmed-meshheading:20885979-Intestinal Mucosa,
pubmed-meshheading:20885979-Mice,
pubmed-meshheading:20885979-NF-kappa B,
pubmed-meshheading:20885979-Random Allocation,
pubmed-meshheading:20885979-Rats,
pubmed-meshheading:20885979-Rats, Sprague-Dawley,
pubmed-meshheading:20885979-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2010
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pubmed:articleTitle |
Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-?B activation.
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pubmed:affiliation |
Department of Gerontology, General Hospital of Guangzhou Military Command of People's Liberation Army, Guangzhou, China. songweibing@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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