20885959

Source:http://linkedlifedata.com/resource/pubmed/id/20885959

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0085187, umls-concept:C0205214, umls-concept:C0205419, umls-concept:C0332281, umls-concept:C0935992, umls-concept:C1444754
pubmed:issue	9
pubmed:dateCreated	2010-10-4
pubmed:abstractText	Telomeres shorten as cells divide. This shortening is compensated by the enzyme telomerase. We evaluated the effect of common variants in the telomerase RNA component (TERC) gene on telomere length (TL) in the population-based Health Aging and Body Composition (Health ABC) Study and in two replication samples (the TwinsUK Study and the Amish Family Osteoporosis Study, AFOS).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/, http://linkedlifedata.com/resource/pubmed/grant/K01 AG022782, http://linkedlifedata.com/resource/pubmed/grant/N01 AG-6-2101, http://linkedlifedata.com/resource/pubmed/grant/N01 AG-6-2103, http://linkedlifedata.com/resource/pubmed/grant/N01 AG-6-2106, http://linkedlifedata.com/resource/pubmed/grant/R01 AG023692, http://linkedlifedata.com/resource/pubmed/grant/R25 CA112355, http://linkedlifedata.com/resource/pubmed/grant/U19 AG023122
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/RNA, http://linkedlifedata.com/resource/pubmed/chemical/Telomerase, http://linkedlifedata.com/resource/pubmed/chemical/telomerase RNA
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:BlackburnElizabeth HEH, pubmed-author:CawthonRichard MRM, pubmed-author:CummingsSteven RSR, pubmed-author:DamcottColeen MCM, pubmed-author:HarrisTamara BTB, pubmed-author:HsuehWen-ChiWC, pubmed-author:KwokPui-YanPY, pubmed-author:ManginoMassimoM, pubmed-author:NewmanAnne BAB, pubmed-author:NjajouOmer TOT, pubmed-author:PawlikowskaLudmilaL, pubmed-author:ShuldinerAlan RAR, pubmed-author:SpectorTimothy DTD, pubmed-author:ValdesAna MAM
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e13048
pubmed:meshHeading	pubmed-meshheading:20885959-Adolescent, pubmed-meshheading:20885959-Adult, pubmed-meshheading:20885959-Aged, pubmed-meshheading:20885959-Aged, 80 and over, pubmed-meshheading:20885959-Aging, pubmed-meshheading:20885959-Body Composition, pubmed-meshheading:20885959-Cohort Studies, pubmed-meshheading:20885959-European Continental Ancestry Group, pubmed-meshheading:20885959-Female, pubmed-meshheading:20885959-Genetic Variation, pubmed-meshheading:20885959-Humans, pubmed-meshheading:20885959-Male, pubmed-meshheading:20885959-Middle Aged, pubmed-meshheading:20885959-Osteoporosis, pubmed-meshheading:20885959-Polymorphism, Single Nucleotide, pubmed-meshheading:20885959-RNA, pubmed-meshheading:20885959-Telomerase, pubmed-meshheading:20885959-Telomere, pubmed-meshheading:20885959-Twins, pubmed-meshheading:20885959-Young Adult
pubmed:year	2010
pubmed:articleTitle	A common variant in the telomerase RNA component is associated with short telomere length.
pubmed:affiliation	Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural, Twin Study, Research Support, N.I.H., Intramural