Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-1-25
pubmed:abstractText
The aim of this work was to establish a new, fast, and robust method of flip-angle calibration for magnetic resonance imaging of hyperpolarized (3) He. The method called flip-angle measurement with magnetization inversion is based on acquiring images from periodically inverted longitudinal magnetization created using the spatial modulation of magnetization technique. By measuring the width of the area where the magnetization was inverted by the spatial modulation of magnetization preparation in phase images, the flip angle can be generated using a simple equation. To validate and establish the limits of the proposed method, flip-angle measurement with magnetization inversion acquisitions were simulated and applied to proton and hyperpolarized (3) He phantoms. Then, the calibration procedure was applied during hyperpolarized (3) He magnetic resonance imaging in a healthy volunteer. The advantage of the flip-angle measurement with magnetization inversion method compared with the conventional method based on the assessment of radiofrequency-decay is that it is free of errors induced by relaxation due to oxygen, by imperfect excitation slice profile and by any diffusion of (3) He into and out of the slice. Another advantage is that it does not require image processing with external software and therefore can be performed using the implemented tools on the magnetic resonance workstation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1522-2594
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
399-408
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Flip-angle measurement by magnetization inversion: Calibration of magnetization nutation angle in hyperpolarized (3) He magnetic resonance imaging lung experiments.
pubmed:affiliation
Section of Medical Physics, Department of Diagnostic and Interventional Radiology, Johannes Gutenberg University Medical Center, Mainz, Germany.
pubmed:publicationType
Journal Article