Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
46
pubmed:dateCreated
2010-11-18
pubmed:abstractText
Interfaces between two immiscible electrolyte solutions are recognized as a simplified model for biological systems and they can be of great relevance to the characterization of biomolecules and their role in biological systems. In this work, ion transfer and facilitated ion transfer of protonated catecholamines (dopamine and noradrenaline) by dibenzo-18-crown-6 are investigated at the water/1,6-dichlorohexane interface. The formation constant of the complex between both dopamine and noradrenaline with dibenzo-18-crown-6 was evaluated and the experimental conditions for the analytical determination of those catecholamines are established. These results can improve the understanding of the pharmacodynamics of the catecholamines, and contribute to the study of their interaction with biological membranes. Furthermore it can be used to develop an alternative method for the determination of neural signal transmission catecholamines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1463-9084
pubmed:author
pubmed:issnType
Electronic
pubmed:day
14
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15190-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Electrochemical study of dopamine and noradrenaline at the water/1,6-dichlorohexane interface.
pubmed:affiliation
Faculdade de Ciências da Universidade do Porto, Departamento de Química e Bioquímica, Centro de Investigação em Química-Linha 4, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't