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20880347
Source:
http://linkedlifedata.com/resource/pubmed/id/20880347
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rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0028754
,
umls-concept:C0030274
,
umls-concept:C0033085
,
umls-concept:C0034693
,
umls-concept:C0205314
,
umls-concept:C0332437
,
umls-concept:C0542341
,
umls-concept:C0679622
,
umls-concept:C1565154
,
umls-concept:C1999216
,
umls-concept:C2353951
,
umls-concept:C2732140
pubmed:issue
11
pubmed:dateCreated
2010-9-30
pubmed:abstractText
To investigate whether glucose lowering with the selective sodium glucose transporter 2 (SGLT2) inhibitor dapagliflozin would prevent or reduce the decline of pancreatic function and disruption of normal islet morphology.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/100883645
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/2-(3-(4-ethoxybenzyl)-4-chlorophenyl...
,
http://linkedlifedata.com/resource/pubmed/chemical/Glucosides
,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Glucose Transporter 2
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1463-1326
pubmed:author
pubmed-author:JonesH BHB
,
pubmed-author:MacdonaldF RFR
,
pubmed-author:MayersR MRM
,
pubmed-author:NeffDD
,
pubmed-author:PoucherS MSM
,
pubmed-author:WestgateLL
,
pubmed-author:WhaleyJ MJM
pubmed:copyrightInfo
© 2010 AstraZeneca UK Ltd.
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1004-12
pubmed:meshHeading
pubmed-meshheading:20880347-Animals
,
pubmed-meshheading:20880347-Diabetes Mellitus, Type 2
,
pubmed-meshheading:20880347-Female
,
pubmed-meshheading:20880347-Glucosides
,
pubmed-meshheading:20880347-Hyperglycemia
,
pubmed-meshheading:20880347-Islets of Langerhans
,
pubmed-meshheading:20880347-Obesity
,
pubmed-meshheading:20880347-Pancreas
,
pubmed-meshheading:20880347-Rats
,
pubmed-meshheading:20880347-Rats, Zucker
,
pubmed-meshheading:20880347-Sodium-Glucose Transporter 2
pubmed:year
2010
pubmed:articleTitle
The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats.
pubmed:affiliation
CVGI Discovery, AstraZeneca, Alderley Park, Macclesfield, Cheshire, UK.
pubmed:publicationType
Journal Article