Source:http://linkedlifedata.com/resource/pubmed/id/20871031
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2010-9-27
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pubmed:abstractText |
Macrophage cells differentiate into killer macrophages, named M1 macrophages, that effectively eliminate cancer cells by generating cytokines. We examined the feasibility of a lung cancer therapy using lipopolysaccharide (LPS), which triggers this differentiation. It is expected that the delivery via inhalation of LPS directly into the lungs, where alveolar macrophages reside abundantly, would be effective at minimizing the possible toxic effect of LPS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1791-7530
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3129-34
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pubmed:meshHeading |
pubmed-meshheading:20871031-Administration, Inhalation,
pubmed-meshheading:20871031-Animals,
pubmed-meshheading:20871031-Antineoplastic Agents,
pubmed-meshheading:20871031-Carcinoma, Lewis Lung,
pubmed-meshheading:20871031-Cyclophosphamide,
pubmed-meshheading:20871031-Drug Synergism,
pubmed-meshheading:20871031-Lipopolysaccharides,
pubmed-meshheading:20871031-Lung Neoplasms,
pubmed-meshheading:20871031-Male,
pubmed-meshheading:20871031-Mice,
pubmed-meshheading:20871031-Mice, Inbred C57BL
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pubmed:year |
2010
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pubmed:articleTitle |
Antitumor effect of inhalatory lipopolysaccharide and synergetic effect in combination with cyclophosphamide.
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pubmed:affiliation |
Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki Noda, Chiba 278-8510, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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