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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1991-5-23
|
| pubmed:abstractText |
Aim of the study was to analyze postprandial lipid changes after an oral fat load (400 g cream) in normal probands (n = 15). In addition we studied the uptake of postprandial VLDL by macrophages. Whereas total cholesterol (Chol), and HDL-chol did not change, plasma triglycerides (TG) (from 91 +/- 37 to 181 +/- 80 mg/dl) and VLDL-TG (from 27 +/- 18 to 41 +/- 26 mg/dl) increased significantly, with a maximum at 3 h after the oral fat load. These changes were interindividually very different and depended neither on lipoprotein or hepatic lipase levels, nor on basic lipid levels. Different post-prandial VLDL-fractions, isolated before or 3 and 6 h after the fat load caused a comparable lipid accumulation in macrophages. It seems very likely that also postprandial lipid elevations may play a role in foam cell generation.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0023-2173
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
68 Suppl 22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
123
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1990
|
| pubmed:articleTitle |
[Increase in triglycerides after fat load in healthy probands].
|
| pubmed:affiliation |
Medizinische Klinik, Universität Heidelberg, Heidelberg.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|