Linked Life Data

20869816

Source:http://linkedlifedata.com/resource/pubmed/id/20869816

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-4
pubmed:dateCreated
2011-2-21
pubmed:abstractText
Porcine circovirus 2 (PCV-2), the essential infectious agent in PCVD (porcine circovirus diseases) circulates at high rates among domestic pig and wild boar populations. Wild boars may be viremic and shed the virus with excretions and secretions, and thus serve as a reservoir for domestic pig PCV-2 infection. We hypothesize that PCV-2 strains circulating in wild boars and in domestic pigs are significantly different and thus, partially independent. To prove this hypothesis, the present study investigated by sequence analysis the distribution of ORF2 and ORF3 genotypes of the PCV-2 genome within wild boars (n=40) and domestic pigs (n=60) from overlapping greater areas of Germany. The genotypes were compared with PCV-2 sequences from the Genbank database. The dominating genotype in domestic pigs was PCV-2b (98.4% of infected pigs), while only 4.8% of them were infected with PCV-2a. The corresponding prevalences of PCV-2a and -2b genotypes in wild boars were 58% and 70%, respectively. When also ORF3 genotypes were taken into account, more than 50% of wild boar PCV-2 genotypes were rare among German and European domestic pigs. In conclusion, these data provide evidence for a certain independence of PCV-2 infections in both species and a low chance for domestic pigs to be infected with PCV-2 of wild boar origin. On the other hand, PCV-2 genotypes specific for domestic pigs are also common in wild boars, although at lower frequencies, suggesting the spread of domestic pig PCV-2 to the wild boar population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1873-2542
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
24
pubmed:volume
148
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
372-6
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Distribution of ORF2 and ORF3 genotypes of porcine circovirus type 2 (PCV-2) in wild boars and domestic pigs in Germany.
pubmed:affiliation
Department of Veterinary Clinical Sciences, Swine Diseases, Frankfurter Strasse 112, Justus-Liebig-University, 35392 Giessen, Germany. gerald.reiner@vetmed.uni-giessen.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't