rdf:type |
|
lifeskim:mentions |
umls-concept:C0005125,
umls-concept:C0012155,
umls-concept:C0015677,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0028754,
umls-concept:C0086982,
umls-concept:C0205132,
umls-concept:C0314603,
umls-concept:C0314657,
umls-concept:C1280500,
umls-concept:C1512692
|
pubmed:dateCreated |
2010-9-22
|
pubmed:abstractText |
The Berlin Fat Mouse Inbred (BFMI) line is a new mouse model for obesity, which was long-term selected for high fatness. Peroxisome proliferator-activated receptors (PPARs) are involved in the control of energy homeostasis, nutrient metabolism and cell proliferation. Here, we studied the expression patterns of the different Ppar genes and the genes in the PPAR pathway in the BFMI line in comparison to physiological changes.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1476-511X
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
99
|
pubmed:meshHeading |
pubmed-meshheading:20831792-Adipose Tissue, White,
pubmed-meshheading:20831792-Animals,
pubmed-meshheading:20831792-Body Constitution,
pubmed-meshheading:20831792-Cell Size,
pubmed-meshheading:20831792-Dietary Fats,
pubmed-meshheading:20831792-Disease Models, Animal,
pubmed-meshheading:20831792-Gene Expression Profiling,
pubmed-meshheading:20831792-Gene Expression Regulation,
pubmed-meshheading:20831792-Genetic Predisposition to Disease,
pubmed-meshheading:20831792-Hypertriglyceridemia,
pubmed-meshheading:20831792-Lipid Metabolism,
pubmed-meshheading:20831792-Liver,
pubmed-meshheading:20831792-Male,
pubmed-meshheading:20831792-Mice,
pubmed-meshheading:20831792-Mice, Inbred Strains,
pubmed-meshheading:20831792-Obesity,
pubmed-meshheading:20831792-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20831792-PPAR alpha,
pubmed-meshheading:20831792-PPAR gamma,
pubmed-meshheading:20831792-RNA, Messenger,
pubmed-meshheading:20831792-Signal Transduction
|
pubmed:year |
2010
|
pubmed:articleTitle |
Genetic and diet effects on Ppar-? and Ppar-? signaling pathways in the Berlin Fat Mouse Inbred line with genetic predisposition for obesity.
|
pubmed:affiliation |
Humboldt-Universität zu Berlin, Department for Crop and Animal Sciences, Invalidenstraße 42, 10115 Berlin, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|