Source:http://linkedlifedata.com/resource/pubmed/id/20817486
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2010-11-1
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pubmed:abstractText |
Chemerin is a secreted protein with a complex but well-established role in immune function. Parallel lines of investigation also support the notion that chemerin is a novel adipokine that regulates adipocyte development and metabolic function as well as glucose metabolism in liver and skeletal muscle tissues. A growing body of human experimental data indicates that serum chemerin levels are elevated in patients with obesity and that they exhibit a positive correlation with various aspects of the metabolic syndrome. Thus, the dual role of chemerin in inflammation and metabolism might provide a link between chronic inflammation and obesity, as well as obesity-related disorders such as type 2 diabetes and cardiovascular disease.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1879-3061
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
660-7
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pubmed:meshHeading |
pubmed-meshheading:20817486-Animals,
pubmed-meshheading:20817486-Cardiovascular Diseases,
pubmed-meshheading:20817486-Chemokines,
pubmed-meshheading:20817486-Glucose,
pubmed-meshheading:20817486-Homeostasis,
pubmed-meshheading:20817486-Humans,
pubmed-meshheading:20817486-Inflammation,
pubmed-meshheading:20817486-Models, Biological,
pubmed-meshheading:20817486-Obesity,
pubmed-meshheading:20817486-Protein Conformation,
pubmed-meshheading:20817486-Protein Processing, Post-Translational
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pubmed:year |
2010
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pubmed:articleTitle |
Chemerin: at the crossroads of inflammation and obesity.
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pubmed:affiliation |
Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada, B3H1X5.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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