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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-9-27
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pubmed:abstractText |
Mutation of the epidermal growth factor receptor (EGFR) gene can predict the efficacy of EGFR-tyrosine kinase inhibitors. Different mutations have been shown to co-occur in a single tumor. However, the frequency of these so-called "complex mutations" and the efficacy of gefitinib in treating patients with these mutations are unclear.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1556-1380
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pubmed:author |
pubmed-author:FujitaShiroS,
pubmed-author:HataAkitoA,
pubmed-author:ImaiYukihiroY,
pubmed-author:IshidaTadashiT,
pubmed-author:IwasakuMasahiroM,
pubmed-author:KajiReikoR,
pubmed-author:KatakamiNobuyukiN,
pubmed-author:KunimasaKeiK,
pubmed-author:NishiyamaAkihiroA,
pubmed-author:TomiiKeisukeK,
pubmed-author:YoshiokaHiroshigeH
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1524-8
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pubmed:meshHeading |
pubmed-meshheading:20808254-Adenocarcinoma,
pubmed-meshheading:20808254-Aged,
pubmed-meshheading:20808254-Aged, 80 and over,
pubmed-meshheading:20808254-Antineoplastic Agents,
pubmed-meshheading:20808254-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20808254-Carcinoma, Squamous Cell,
pubmed-meshheading:20808254-DNA, Neoplasm,
pubmed-meshheading:20808254-Female,
pubmed-meshheading:20808254-Humans,
pubmed-meshheading:20808254-Lung Neoplasms,
pubmed-meshheading:20808254-Male,
pubmed-meshheading:20808254-Middle Aged,
pubmed-meshheading:20808254-Point Mutation,
pubmed-meshheading:20808254-Polymerase Chain Reaction,
pubmed-meshheading:20808254-Prognosis,
pubmed-meshheading:20808254-Quinazolines,
pubmed-meshheading:20808254-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20808254-Sequence Deletion
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pubmed:year |
2010
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pubmed:articleTitle |
Complex mutations in the epidermal growth factor receptor gene in non-small cell lung cancer.
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pubmed:affiliation |
Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Chuo-ku, Kobe, Japan.
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pubmed:publicationType |
Journal Article
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