Linked Life Data

2080705

Source:http://linkedlifedata.com/resource/pubmed/id/2080705

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-5-1
pubmed:abstractText
In diabetes mellitus, the retina is exposed to fluctuations in blood glucose concentrations, presumed decreases in oxygen availability and other metabolic disturbances induced by the disease. These metabolic phenomena may play a role in diabetic retinopathy. To understand these processes better, we measured oxygen consumption in vitro in retinas from normal and diabetic rabbits and examined the effect of oxygen and glucose concentration on retinal respiration. Retinal oxygen consumption is decreased in diabetic retinas compared to normal rabbit retinas (0.56 +/- 0.09 ml of oxygen per min per mg dry weight in normal and 0.40 +/- 0.07 ml of oxygen per min per mg dry weight in diabetic retinas). Retinal oxygen consumption is elevated if the oxygen tension is raised above normal in both groups. Glucose concentration did not significantly effect the oxygen consumption of the retina in either group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0001-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
715-20
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Retinal oxygen consumption in vitro. The effect of diabetes mellitus, oxygen and glucose.
pubmed:affiliation
Duke University Medical Center, Department of Ophthalmology, Durham, North Carolina.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't