rdf:type |
|
lifeskim:mentions |
umls-concept:C0020517,
umls-concept:C0026336,
umls-concept:C0087111,
umls-concept:C0339805,
umls-concept:C0392756,
umls-concept:C0700624,
umls-concept:C0871261,
umls-concept:C1522424,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
2
|
pubmed:dateCreated |
2011-1-6
|
pubmed:abstractText |
? A hypoallergen of the major cat allergen Fel d 1, recombinant (r) Fel d 1 (DTE III), was previously shown to have retained T-cell reactivity and strongly reduced IgE-binding capacity compared to unmodified rFel d 1. Here, we evaluated the therapeutic capacity of rFel?d 1 (DTE III) in a mouse model for cat allergy.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1398-9995
|
pubmed:author |
|
pubmed:copyrightInfo |
© 2010 John Wiley & Sons A/S.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
66
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
255-63
|
pubmed:meshHeading |
pubmed-meshheading:20804464-Animals,
pubmed-meshheading:20804464-Antigen-Antibody Reactions,
pubmed-meshheading:20804464-Case-Control Studies,
pubmed-meshheading:20804464-Cats,
pubmed-meshheading:20804464-Disease Models, Animal,
pubmed-meshheading:20804464-Glycoproteins,
pubmed-meshheading:20804464-Humans,
pubmed-meshheading:20804464-Hypersensitivity,
pubmed-meshheading:20804464-Immunoglobulin E,
pubmed-meshheading:20804464-Immunoglobulin G,
pubmed-meshheading:20804464-Immunotherapy,
pubmed-meshheading:20804464-Mice,
pubmed-meshheading:20804464-Recombinant Proteins,
pubmed-meshheading:20804464-Treatment Outcome
|
pubmed:year |
2011
|
pubmed:articleTitle |
Treatment with a Fel d 1 hypoallergen reduces allergic responses in a mouse model for cat allergy.
|
pubmed:affiliation |
Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden. tiiu.saarne@ki.se
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|