| pubmed-article:20801040 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C0175677 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C0037925 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C0009938 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:20801040 | lifeskim:mentions | umls-concept:C1517004 | lld:lifeskim |
| pubmed-article:20801040 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:20801040 | pubmed:dateCreated | 2010-11-1 | lld:pubmed |
| pubmed-article:20801040 | pubmed:abstractText | The purpose of this study was to investigate the early effects of granulocyte-colony stimulating factor (G-CSF) on myeloperoxidase (MPO) activity, lipid peroxidation (LPO) and ultrastructural findings in rats after spinal cord injury (SCI). We also compared the effects of G-CSF and methylprednisolone sodium succinate (MPSS). Wistar rats were divided into four groups: control, SCI alone (50 g/cm weight drop trauma), SCI+MPSS (30 mg/kg), and SCI+G-CSF (50 ?g/kg). Administration of G-CSF and MPSS significantly decreased LPO (p < 0.05) and MPO activity (p < 0.05) in the first 24 hours. MPSS was more effective than G-CSF in reducing LPO (p < 0.05) and in minimizing ultrastructure changes. The results of this study indicate that G-CSF exerts a beneficial effect by decreasing MPO activity and LPO and may reduce tissue damage in the first 24 hours after SCI. Our findings do not exclude the possibility that G-CSF has a protective effect on spinal cord ultrastructure after the first 24 hours following SCI. | lld:pubmed |
| pubmed-article:20801040 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20801040 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20801040 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20801040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20801040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20801040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20801040 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20801040 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20801040 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:20801040 | pubmed:issn | 1532-2653 | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:SargonMustafa... | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:KilinçKamerK | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:SekerciZekiZ | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:Kaptano?luErk... | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:SerbesGökhanG | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:SanliA... | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:Be?altiOmerO | lld:pubmed |
| pubmed-article:20801040 | pubmed:author | pubmed-author:Cali?kanMurat... | lld:pubmed |
| pubmed-article:20801040 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20801040 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20801040 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:20801040 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20801040 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20801040 | pubmed:pagination | 1548-52 | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:meshHeading | pubmed-meshheading:20801040... | lld:pubmed |
| pubmed-article:20801040 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20801040 | pubmed:articleTitle | Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury. | lld:pubmed |
| pubmed-article:20801040 | pubmed:affiliation | Department of Neurosurgery, Di?kapi Yildir?m Beyazit Research and Education Hospital, Ankara, Turkey. ahmetmetinsanli@hotmail.com | lld:pubmed |
| pubmed-article:20801040 | pubmed:publicationType | Journal Article | lld:pubmed |
