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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1978-8-28
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pubmed:abstractText |
Serial concomitant paired sera (S) and CSF were taken from eight patients with biopsy-proved herpes simplex virus encephalitis (HSVE). These specimen pairs were compared with 28 others from patients with various neurologic conditions. Before and after reduction with 2-mercaptoethanol, a ratio of S/CSF antibody titers of less than or equal to 20 with either the passive hemagglutinating (PHA) or immune adherence hemagglutinating (IAHA) antibody tests occurred in every patient with HSVE. Diagnostic S/CSF ratios were noted in three patients before biopsy of the brain and in four patients by the tenth day of neurologic disease. Among control subjects, a ratio of S/CSF titers greater than 20 was observed in all but four patients. Each of the latter patients had neurologic diagnoses easily distinguishable from HSVE. The PHA or IAHA S/CSF ratio offers a rapid, reliable method for the diagnosis of HSVE (P less than .001).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0098-7484
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
240
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
356-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:207906-Adult,
pubmed-meshheading:207906-Antibodies, Viral,
pubmed-meshheading:207906-Biopsy,
pubmed-meshheading:207906-Brain,
pubmed-meshheading:207906-Encephalitis,
pubmed-meshheading:207906-Female,
pubmed-meshheading:207906-Hemagglutination Tests,
pubmed-meshheading:207906-Herpes Simplex,
pubmed-meshheading:207906-Humans,
pubmed-meshheading:207906-Immune Adherence Reaction,
pubmed-meshheading:207906-Male,
pubmed-meshheading:207906-Simplexvirus
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pubmed:year |
1978
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pubmed:articleTitle |
Simultaneous serum and CSF antibodies in herpes simplex virus encephalitis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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