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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2010-10-21
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pubmed:abstractText |
Patients with light chain (AL) amyloidosis who present with severe heart failure due to cardiac involvement rarely survive more than 6 months. Survival after cardiac transplantation is markedly reduced due to the progression of amyloidosis. Autologous stem-cell transplantation (ASCT) has become a common therapy for AL amyloidosis, but there is an exceedingly high treatment-related mortality in patients with heart failure.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1534-6080
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pubmed:author |
pubmed-author:AttarEyalE,
pubmed-author:BallenKarenK,
pubmed-author:ChungStephen SSS,
pubmed-author:DeyBimalangshu RBR,
pubmed-author:MacgillivrayThomas ETE,
pubmed-author:MadsenJoren CJC,
pubmed-author:McAfeeStevenS,
pubmed-author:MooreStephanieS,
pubmed-author:Newton-ChehChristopherC,
pubmed-author:SanchorawalaVaishaliV,
pubmed-author:SeldinDavid CDC,
pubmed-author:SemigranMarc JMJ,
pubmed-author:ShinJordanJ,
pubmed-author:SkinnerMarthaM,
pubmed-author:SpitzerThomas RTR,
pubmed-author:WangThomasT,
pubmed-author:ZhengHuiH
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
905-11
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:20733534-Adult,
pubmed-meshheading:20733534-Aged,
pubmed-meshheading:20733534-Alanine,
pubmed-meshheading:20733534-Amyloidosis,
pubmed-meshheading:20733534-Aspartate Aminotransferases,
pubmed-meshheading:20733534-Cardiotonic Agents,
pubmed-meshheading:20733534-Female,
pubmed-meshheading:20733534-Heart Failure,
pubmed-meshheading:20733534-Heart Transplantation,
pubmed-meshheading:20733534-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:20733534-Humans,
pubmed-meshheading:20733534-Male,
pubmed-meshheading:20733534-Melphalan,
pubmed-meshheading:20733534-Middle Aged,
pubmed-meshheading:20733534-Stem Cell Transplantation,
pubmed-meshheading:20733534-Stroke Volume,
pubmed-meshheading:20733534-Transplantation, Autologous
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pubmed:year |
2010
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pubmed:articleTitle |
Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure.
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pubmed:affiliation |
Massachusetts General Hospital, Boston, MA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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