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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-8-20
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pubmed:abstractText |
Hematopoietic chimerism induces transplantation tolerance across allogeneic and xenogeneic barriers, but has been difficult to achieve in the pig-to-primate model. We have now utilized swine with knockout of the gene coding for alpha-1,3-galactosyltransferase (GalT-KO pigs) as bone marrow donors in an attempt to achieve chimerism and tolerance by avoiding the effects of natural antibodies to Gal determinants on pig hematopoietic cells.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-10221480,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-10355729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-10609947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-10642595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-10868629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-11435972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-11548840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-11680007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-11740385,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-11778012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-11792972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-12060466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-12777846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-15123792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-15196131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-15714161,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-16796719,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-1695393,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-17294522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-18216355,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-1901297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-1972728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-2382234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-2562984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-3122383,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-3871107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-6609988,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-7839449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-7858524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-8560550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-9254648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-9278321,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20723202-9701260
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1399-3089
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2010 John Wiley & Sons A/S.
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
300-12
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pubmed:dateRevised |
2011-8-1
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pubmed:meshHeading |
pubmed-meshheading:20723202-Animals,
pubmed-meshheading:20723202-Antibodies,
pubmed-meshheading:20723202-Antigens,
pubmed-meshheading:20723202-Bone Marrow,
pubmed-meshheading:20723202-Bone Marrow Transplantation,
pubmed-meshheading:20723202-Galactosyltransferases,
pubmed-meshheading:20723202-Gene Knockout Techniques,
pubmed-meshheading:20723202-Humans,
pubmed-meshheading:20723202-Papio,
pubmed-meshheading:20723202-Rabbits,
pubmed-meshheading:20723202-Rats,
pubmed-meshheading:20723202-Swine,
pubmed-meshheading:20723202-Transplantation, Heterologous,
pubmed-meshheading:20723202-Transplantation Chimera,
pubmed-meshheading:20723202-Transplantation Conditioning
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pubmed:articleTitle |
Occurrence of specific humoral non-responsiveness to swine antigens following administration of GalT-KO bone marrow to baboons.
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pubmed:affiliation |
Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
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pubmed:publicationType |
Journal Article
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