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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-8-16
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pubmed:abstractText |
The vitamin D dependent intestinal calcium-binding protein (calbindin-D9K) was measured by an enzyme-linked immunoadsorbent assay in small intestinal biopsy specimens from 10 children (aged 15-126 months). The aim was to study the relationship between calcium-binding protein and age, bone age, and height. The patients were examined due to complaints of chronic diarrhea, but no evidence of malabsorption was found. The amount of calbindin-D9K per mg of soluble protein in the small intestinal biopsy specimens was higher than previously studied in normal adults. Calbindin-D9K correlated inversely with chronological age, bone age, and height of the children (p = -0.87, rho = -0.66, and rho = -0.66; p less than 0.05). A direct correlation was found between calbindin-D9K and intestinal alkaline phosphatase activity (p = 0.60; p less than 0.05). The decline in calbindin-D9K may indicate that the active vitamin D dependent intestinal calcium absorption decreases during childhood.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0277-2116
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
328-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2072223-Age Determination by Skeleton,
pubmed-meshheading:2072223-Age Factors,
pubmed-meshheading:2072223-Biopsy,
pubmed-meshheading:2072223-Body Height,
pubmed-meshheading:2072223-Calcium-Binding Protein, Vitamin D-Dependent,
pubmed-meshheading:2072223-Child,
pubmed-meshheading:2072223-Child, Preschool,
pubmed-meshheading:2072223-Female,
pubmed-meshheading:2072223-Humans,
pubmed-meshheading:2072223-Infant,
pubmed-meshheading:2072223-Intestine, Small,
pubmed-meshheading:2072223-Male
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pubmed:year |
1991
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pubmed:articleTitle |
Measurement of calbindin-D9K in small intestinal biopsy specimens of children.
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pubmed:affiliation |
Department of Medicine A, Rigshospitalet, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|