Linked Life Data

20672171

Source:http://linkedlifedata.com/resource/pubmed/id/20672171

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-9-29
pubmed:abstractText
Green Fluorescent Protein (GFP) and other related fluorescent proteins are generally used as genetically encoded, chemically inert labels in vivo. This review focuses on the emerging application of fluorescent proteins as light-inducible intracellular photochemical partners. The first example of a chemically active GFP-like protein was the phototoxic red fluorescent protein KillerRed, which can be used for precise light-induced killing of cells, protein inactivation, and studying reactive oxygen species signaling in different cellular compartments. Moreover, recent studies revealed that various GFPs can act as light-induced electron donors in photochemical reactions with biologically relevant electron acceptors. These findings have important implications for practical uses of fluorescent proteins as well as for our understanding of the evolution and biology of this protein family.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1474-9092
pubmed:author
pubmed:issnType
Electronic
pubmed:day
28
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1301-6
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Fluorescent proteins as light-inducible photochemical partners.
pubmed:affiliation
Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997, Moscow, Russia. kluk@ibch.ru
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't