Source:http://linkedlifedata.com/resource/pubmed/id/20671972
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2010-7-30
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pubmed:abstractText |
CONJUGATES OF PURINE AND PYRIMIDINE NUCLEOSIDES: thymidine and 2'-deoxyguanosine with cobalt-metallacarborane were studied for their sodium ion complexing properties. Formation of stable complexes of 1 : 1 stoichiometry was proved by ESI MS spectroscopy and (23)Na NMR. Equilibrium constants and energies of complex formation were calculated. Complexation of alkali-metals by nucleoside-metallacarborane conjugates may affect the physicochemical and biological properties of the conjugates and should be taken into consideration during biological evaluation of these types of modifications.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-1272809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-15752983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-15878666,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-16287247,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-16369936,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-18598016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20671972-18803374
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pubmed:language |
eng
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:issn |
1687-479X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196064
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pubmed:year |
2010
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pubmed:articleTitle |
The effect of stereochemistry on sodium ion complexation in nucleoside-metallacarborane conjugates.
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pubmed:affiliation |
Laboratory of Molecular Virology and Biological Chemistry, Institute for Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 ?ód?, Poland.
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pubmed:publicationType |
Journal Article
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