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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-7-30
pubmed:abstractText
CONJUGATES OF PURINE AND PYRIMIDINE NUCLEOSIDES: thymidine and 2'-deoxyguanosine with cobalt-metallacarborane were studied for their sodium ion complexing properties. Formation of stable complexes of 1 : 1 stoichiometry was proved by ESI MS spectroscopy and (23)Na NMR. Equilibrium constants and energies of complex formation were calculated. Complexation of alkali-metals by nucleoside-metallacarborane conjugates may affect the physicochemical and biological properties of the conjugates and should be taken into consideration during biological evaluation of these types of modifications.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1687-479X
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
196064
pubmed:year
2010
pubmed:articleTitle
The effect of stereochemistry on sodium ion complexation in nucleoside-metallacarborane conjugates.
pubmed:affiliation
Laboratory of Molecular Virology and Biological Chemistry, Institute for Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 ?ód?, Poland.
pubmed:publicationType
Journal Article