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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-11-1
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pubmed:abstractText |
The deregulation of several transcription factors contribute to the aggressive course of mantle cell lymphoma. This study focuses on survival signals emanating from the tumor environment and involving the signal transducer and activator of transcription (STAT) 3 through cytokines or antigen recognition.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Boronic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/IL10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/IL6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Protease Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazines,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, B-Cell,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/bortezomib
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1592-8721
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pubmed:author |
pubmed-author:Ajchenbaum-CymbalistaFlorenceF,
pubmed-author:Baran-MarszakFannyF,
pubmed-author:BoukhiarMohandM,
pubmed-author:FagardRemiR,
pubmed-author:GressinRemyR,
pubmed-author:HarelStéphanieS,
pubmed-author:LaguillierChristelleC,
pubmed-author:LedouxDominiqueD,
pubmed-author:MartinAntoineA,
pubmed-author:RogerClaudineC,
pubmed-author:Varin-BlankNadineN
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pubmed:issnType |
Electronic
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1865-72
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pubmed:meshHeading |
pubmed-meshheading:20663948-Aged,
pubmed-meshheading:20663948-Aged, 80 and over,
pubmed-meshheading:20663948-Autocrine Communication,
pubmed-meshheading:20663948-Boronic Acids,
pubmed-meshheading:20663948-Cell Line, Tumor,
pubmed-meshheading:20663948-Cell Survival,
pubmed-meshheading:20663948-Female,
pubmed-meshheading:20663948-Humans,
pubmed-meshheading:20663948-Interleukin-10,
pubmed-meshheading:20663948-Interleukin-6,
pubmed-meshheading:20663948-Janus Kinases,
pubmed-meshheading:20663948-Lymphoma, Mantle-Cell,
pubmed-meshheading:20663948-Male,
pubmed-meshheading:20663948-Middle Aged,
pubmed-meshheading:20663948-Phosphorylation,
pubmed-meshheading:20663948-Protease Inhibitors,
pubmed-meshheading:20663948-Pyrazines,
pubmed-meshheading:20663948-Receptors, Antigen, B-Cell,
pubmed-meshheading:20663948-STAT3 Transcription Factor,
pubmed-meshheading:20663948-Signal Transduction
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pubmed:year |
2010
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pubmed:articleTitle |
Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma.
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pubmed:affiliation |
INSERM U978, Bobigny, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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