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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-8-16
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pubmed:abstractText |
Histone deacetylase (HDAC) inhibitors are a novel anti-tumor therapy. To determine whether HDAC inhibitors may be useful in the treatment of adult acute lymphoblastic leukemia (ALL), we examined the acetylation of histone H4 by immunohistochemistry in newly diagnosed ALL patients and evaluated the impact of acetylation on complete remission (CR) rate, relapse-free survival (RFS), and overall survival (OS).
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-10339508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-11309347,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-12429021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-12724214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-14734806,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-15770522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-15988529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-17827453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-18413789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-3422030,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20663136-7718875
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
pubmed-author:AdvaniAnjali SAS,
pubmed-author:CopelanEdE,
pubmed-author:DouglasElizabethE,
pubmed-author:GibsonSarah ESE,
pubmed-author:HsiEric DED,
pubmed-author:KalaycioMattM,
pubmed-author:LEVILa LLL,
pubmed-author:SekeresMikkaelM,
pubmed-author:SobecksRonaldR,
pubmed-author:SungrenShawndaS,
pubmed-author:ZhaoXiaoxianX
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
387
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pubmed:meshHeading |
pubmed-meshheading:20663136-Acetylation,
pubmed-meshheading:20663136-Adolescent,
pubmed-meshheading:20663136-Adult,
pubmed-meshheading:20663136-Biopsy,
pubmed-meshheading:20663136-Blotting, Western,
pubmed-meshheading:20663136-Bone Marrow,
pubmed-meshheading:20663136-Butyrates,
pubmed-meshheading:20663136-Cells, Cultured,
pubmed-meshheading:20663136-Histones,
pubmed-meshheading:20663136-Humans,
pubmed-meshheading:20663136-Immunoenzyme Techniques,
pubmed-meshheading:20663136-Middle Aged,
pubmed-meshheading:20663136-Neoplasm Recurrence, Local,
pubmed-meshheading:20663136-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:20663136-Prognosis,
pubmed-meshheading:20663136-Remission Induction,
pubmed-meshheading:20663136-Survival Rate,
pubmed-meshheading:20663136-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Histone H4 acetylation by immunohistochemistry and prognosis in newly diagnosed adult acute lymphoblastic leukemia (ALL) patients.
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pubmed:affiliation |
Department of Hematologic Oncology and Blood Disorders, Taussig Cancer Center, The Cleveland Clinic, Cleveland, OH, USA. advania@ccf.org
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pubmed:publicationType |
Journal Article
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