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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-10-20
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pubmed:abstractText |
To investigate the role of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in postoperative polymicrobial abdominal sepsis.Sepsis is the leading cause of death among critically ill surgical patients. TRAIL is commonly known as an apoptosis-inducing agent in cancer cells. It also plays an important role in the regulation of inflammatory reactions. The role of TRAIL in polymicrobial sepsis is still unclear.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1530-0293
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pubmed:author |
pubmed-author:BrökerBarbara MBM,
pubmed-author:BusemannAlexandraA,
pubmed-author:CziupkaKatharinaK,
pubmed-author:DiedrichStephanS,
pubmed-author:HeideckeClaus-DieterCD,
pubmed-author:KesslerWolframW,
pubmed-author:KoernerPiaP,
pubmed-author:MaierStefanS,
pubmed-author:PötschkeChristianC,
pubmed-author:ParteckeLars IvoLI,
pubmed-author:RathMatthiasM,
pubmed-author:TraegerTobiasT,
pubmed-author:WeissFrank UlrichFU,
pubmed-author:von BernstorffWolframW
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2169-74
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pubmed:meshHeading |
pubmed-meshheading:20657274-Animals,
pubmed-meshheading:20657274-Apoptosis,
pubmed-meshheading:20657274-Chemokines,
pubmed-meshheading:20657274-Cytokines,
pubmed-meshheading:20657274-Disease Models, Animal,
pubmed-meshheading:20657274-Female,
pubmed-meshheading:20657274-Immunity, Innate,
pubmed-meshheading:20657274-Injections, Intravenous,
pubmed-meshheading:20657274-Mice,
pubmed-meshheading:20657274-Mice, Inbred C57BL,
pubmed-meshheading:20657274-Neutrophil Infiltration,
pubmed-meshheading:20657274-Neutrophils,
pubmed-meshheading:20657274-Peritoneal Cavity,
pubmed-meshheading:20657274-Peritonitis,
pubmed-meshheading:20657274-Receptors, TNF-Related Apoptosis-Inducing Ligand,
pubmed-meshheading:20657274-Recombinant Proteins,
pubmed-meshheading:20657274-Sepsis,
pubmed-meshheading:20657274-TNF-Related Apoptosis-Inducing Ligand
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pubmed:year |
2010
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pubmed:articleTitle |
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) improves the innate immune response and enhances survival in murine polymicrobial sepsis.
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pubmed:affiliation |
Department of Surgery, Ernst-Moritz-Arndt University Greifswald, Germany. cziupka@uni-greifswald.de
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pubmed:publicationType |
Journal Article
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