Source:http://linkedlifedata.com/resource/pubmed/id/20655708
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-8-27
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pubmed:abstractText |
Temporal lobe epilepsy (TLE) is the most common epilepsy and about 30% of patients have poorly controlled seizures. Neurobiology underlying responsiveness to medical treatment in TLE patients is unclear and there are currently no biological tests to predict course of the disease. Animal and human studies repeatedly suggested serotonergic dysfunction in subjects with TLE. We investigated association of serotonin transporter (5-HTT) gene polymorphisms with medical treatment response in patients with TLE.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1872-6844
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-8
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pubmed:meshHeading |
pubmed-meshheading:20655708-Adolescent,
pubmed-meshheading:20655708-Adult,
pubmed-meshheading:20655708-Anticonvulsants,
pubmed-meshheading:20655708-Epilepsy, Temporal Lobe,
pubmed-meshheading:20655708-Female,
pubmed-meshheading:20655708-Genome-Wide Association Study,
pubmed-meshheading:20655708-Humans,
pubmed-meshheading:20655708-Introns,
pubmed-meshheading:20655708-Male,
pubmed-meshheading:20655708-Middle Aged,
pubmed-meshheading:20655708-Minisatellite Repeats,
pubmed-meshheading:20655708-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:20655708-Treatment Outcome,
pubmed-meshheading:20655708-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Association of serotonin transporter promoter (5-HTTLPR) and intron 2 (VNTR-2) polymorphisms with treatment response in temporal lobe epilepsy.
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pubmed:affiliation |
Zagreb Epilepsy Center, Department of Neurology, University Hospital, Vinogradska 29, HR-10000 Zagreb, Croatia. Hecimovic@inet.hr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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