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pubmed-article:20638672pubmed:abstractTextOur recent work demonstrated that treatment of neuroblastoma with triptolide causes apoptotic cell death in vitro and decreases tumor size in vivo. Triptolide therapy has been associated with reduced expression of Hsp-70, suggesting a mechanism of cell killing involving Hsp-70 inhibition. The principal objective of this study was to investigate the role of Hsp-70 in triptolide-mediated cell death in neuroblastoma.lld:pubmed
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pubmed-article:20638672pubmed:copyrightInfoCopyright 2010 Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:20638672pubmed:articleTitleRole of Hsp-70 in triptolide-mediated cell death of neuroblastoma.lld:pubmed
pubmed-article:20638672pubmed:affiliationDepartment of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA. antonoff@umn.edulld:pubmed
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pubmed-article:20638672pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed