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pubmed-article:20621728pubmed:abstractTextA novel series of pyrrole inhibitors of MEK kinase has been developed using structure-based drug design. Optimization of the series led to the identification of potent inhibitors with good pharmaceutical properties.lld:pubmed
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pubmed-article:20621728pubmed:copyrightInfo2010 Elsevier Ltd. All rights reserved.lld:pubmed
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pubmed-article:20621728pubmed:articleTitleStructure-based design and synthesis of pyrrole derivatives as MEK inhibitors.lld:pubmed
pubmed-article:20621728pubmed:affiliationTakeda San Diego, 10410 Science Center Drive, San Diego, CA 92121, United States. michael.wallace@takedasd.comlld:pubmed
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