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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-9-30
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pubmed:abstractText |
To investigate whether a super-high dose (SHD) of methylprednisolone (MP) improves its efficacy or induces glucocorticoid (GC) resistance, and to explore the potential mechanisms of GC resistance in experimental allergic encephalomyelitis (EAE).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0216
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
28-36
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pubmed:meshHeading |
pubmed-meshheading:20616573-Animals,
pubmed-meshheading:20616573-Cytokines,
pubmed-meshheading:20616573-Dose-Response Relationship, Drug,
pubmed-meshheading:20616573-Dose-Response Relationship, Immunologic,
pubmed-meshheading:20616573-Drug Resistance,
pubmed-meshheading:20616573-Encephalomyelitis, Autoimmune, Experimental,
pubmed-meshheading:20616573-Female,
pubmed-meshheading:20616573-Guinea Pigs,
pubmed-meshheading:20616573-Male,
pubmed-meshheading:20616573-Methylprednisolone,
pubmed-meshheading:20616573-Nuclear Proteins,
pubmed-meshheading:20616573-Protein Isoforms,
pubmed-meshheading:20616573-RNA-Binding Proteins,
pubmed-meshheading:20616573-Rats,
pubmed-meshheading:20616573-Rats, Wistar,
pubmed-meshheading:20616573-Receptors, Glucocorticoid,
pubmed-meshheading:20616573-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Super-high-dose methylprednisolone does not improve efficacy or induce glucocorticoid resistance in experimental allergic encephalomyelitis.
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pubmed:affiliation |
Department of Neurology, First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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