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pubmed-article:20606741pubmed:abstractTextProtein carbonylation is an irreversible and not reparable reaction which is caused by the introduction into proteins of carbonyl derivatives such as ketones and aldehydes, generated from direct oxidation processes or from secondary protein reaction with reactive carbonyl compounds. Several studies have demonstrated significantly increased levels of reactive carbonyl compounds, a general increase in plasma protein carbonyls and carbonyl formation on major plasma proteins in blood from uremic patients, particularly those undergoing chronic haemodialysis.lld:pubmed
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pubmed-article:20606741pubmed:articleTitleAdsorption and carbonylation of plasma proteins by dialyser membrane material: in vitro and in vivo proteomics investigations.lld:pubmed
pubmed-article:20606741pubmed:affiliationCentre of Investigation on Aging (Ce.S.I.), G. d'Annunzio University Foundation, Chieti-Pescara, Rome.lld:pubmed
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