Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1991-8-5
|
pubmed:abstractText |
The somatostatin analogue, ectrootide, is being used to treat postprandial hypotension in patients with autonomic neuropathy. Although the therapeutic effect of the drug is presumably secondary to a splanchnic vasoconstrictor action, its effect on splanchnic hemodynamics has never been characterized in patients with autonomic neuropathy. Moreover, it is unknown whether octreotide acts on other vascular beds in this group of patients or whether it affects cardiac output. We, therefore, measured splanchnic, forearm, and systemic vascular resistance and cardiac output before and after administering octreotide (0.4 microgram/kg s.c.) to patients with idiopathic autonomic neuropathy and diabetic autonomic neuropathy.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0009-7322
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
84
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
168-76
|
pubmed:dateRevised |
2010-3-24
|
pubmed:meshHeading |
pubmed-meshheading:2060092-Adolescent,
pubmed-meshheading:2060092-Adult,
pubmed-meshheading:2060092-Aged,
pubmed-meshheading:2060092-Aged, 80 and over,
pubmed-meshheading:2060092-Autonomic Nervous System Diseases,
pubmed-meshheading:2060092-Cardiac Output,
pubmed-meshheading:2060092-Dihydroergotamine,
pubmed-meshheading:2060092-Eating,
pubmed-meshheading:2060092-Female,
pubmed-meshheading:2060092-Forearm,
pubmed-meshheading:2060092-Humans,
pubmed-meshheading:2060092-Hypotension,
pubmed-meshheading:2060092-Male,
pubmed-meshheading:2060092-Middle Aged,
pubmed-meshheading:2060092-Octreotide,
pubmed-meshheading:2060092-Splanchnic Circulation,
pubmed-meshheading:2060092-Vascular Resistance
|
pubmed:year |
1991
|
pubmed:articleTitle |
Hemodynamic effects of octreotide in patients with autonomic neuropathy.
|
pubmed:affiliation |
General Clinical Research Center, Temple University Hospital, Philadelphia.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|