rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-10-4
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pubmed:abstractText |
Lsc/p115 originally was described as hematopoietic Ras homologous protein guanine exchange factor (Rho-GEF) regulating leukocyte migration, adhesion, and marginal zone B-cell homeostasis. Here we investigate the expression pattern of lsc/p115 in the gastrointestinal tract and the consequences of lsc/p115 deficiency in lsc/p115-knockout mice.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1344-54
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pubmed:dateRevised |
2011-4-20
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pubmed:meshHeading |
pubmed-meshheading:20600037-Animals,
pubmed-meshheading:20600037-Esophageal Achalasia,
pubmed-meshheading:20600037-Esophageal Sphincter, Lower,
pubmed-meshheading:20600037-Esophagus,
pubmed-meshheading:20600037-Guanine Nucleotide Exchange Factors,
pubmed-meshheading:20600037-Mice,
pubmed-meshheading:20600037-Mice, Knockout,
pubmed-meshheading:20600037-Nerve Growth Factor,
pubmed-meshheading:20600037-Nerve Tissue Proteins,
pubmed-meshheading:20600037-Neurites,
pubmed-meshheading:20600037-Neurons,
pubmed-meshheading:20600037-Phenotype,
pubmed-meshheading:20600037-Proto-Oncogene Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Loss of Lsc/p115 protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice.
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pubmed:affiliation |
Department of Internal Medicine I, Center of Internal Medicine, University Ulm, Ulm, Germany.
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pubmed:publicationType |
Journal Article
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