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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-8-16
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pubmed:abstractText |
Depression, a disease usually accompanied by a serotonergic deficit, has been observed in about 40% of patients suffering from Parkinson's disease (PD). Thus, a serotonergic dysfunction in PD can be assumed. We aimed to investigate the interaction between serotonergic (5-HT) and dopaminergic activity in early PD. We hypothesized a serotonergic as well as a dopaminergic deficit in PD patients. We also assumed a correlation between these neurotransmitters indicating a relationship between dopaminergic and serotonergic function in PD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1814-1412
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
781-7
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pubmed:meshHeading |
pubmed-meshheading:20586535-Aged,
pubmed-meshheading:20586535-Depressive Disorder,
pubmed-meshheading:20586535-Dopamine Plasma Membrane Transport Proteins,
pubmed-meshheading:20586535-Evoked Potentials, Auditory,
pubmed-meshheading:20586535-Female,
pubmed-meshheading:20586535-Humans,
pubmed-meshheading:20586535-Levodopa,
pubmed-meshheading:20586535-Male,
pubmed-meshheading:20586535-Membrane Transport Proteins,
pubmed-meshheading:20586535-Middle Aged,
pubmed-meshheading:20586535-Parkinson Disease,
pubmed-meshheading:20586535-Pilot Projects,
pubmed-meshheading:20586535-Receptors, Serotonin,
pubmed-meshheading:20586535-Serotonin,
pubmed-meshheading:20586535-Synaptic Transmission,
pubmed-meshheading:20586535-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
2010
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pubmed:articleTitle |
Serotonergic neurotransmission in early Parkinson's disease: a pilot study to assess implications for depression in this disorder.
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pubmed:affiliation |
Department of Clinical Psychology, Humboldt University, Berlin, Germany.
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pubmed:publicationType |
Journal Article
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