rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-9-3
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pubmed:abstractText |
A new PET ligand, 3-fluoro-5-(2-(2-(18)F-(fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ((18)F-SP203), is a positron emission tomographic radioligand selective for metabotropic glutamate subtype 5 receptors. The purposes of this study were to estimate the radiation-absorbed doses of (18)F-SP203 in humans and to determine from the distribution of radioactivity in bone structures with various proportions of bone and red marrow whether (18)F-SP203 undergoes defluorination.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1619-7089
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1943-9
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pubmed:dateRevised |
2011-11-3
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pubmed:meshHeading |
pubmed-meshheading:20585776-Adult,
pubmed-meshheading:20585776-Bone Marrow,
pubmed-meshheading:20585776-Bone and Bones,
pubmed-meshheading:20585776-Female,
pubmed-meshheading:20585776-Fluorine Radioisotopes,
pubmed-meshheading:20585776-Halogenation,
pubmed-meshheading:20585776-Humans,
pubmed-meshheading:20585776-Ligands,
pubmed-meshheading:20585776-Male,
pubmed-meshheading:20585776-Nitriles,
pubmed-meshheading:20585776-Positron-Emission Tomography,
pubmed-meshheading:20585776-Radiation Dosage,
pubmed-meshheading:20585776-Radiometry,
pubmed-meshheading:20585776-Receptors, Metabotropic Glutamate,
pubmed-meshheading:20585776-Thiazoles
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pubmed:year |
2010
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pubmed:articleTitle |
Biodistribution and radiation dosimetry of a positron emission tomographic ligand, 18F-SP203, to image metabotropic glutamate subtype 5 receptors in humans.
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pubmed:affiliation |
Molecular Imaging Branch, National Institute of Mental Health, 10 Center Drive, Bethesda, MD 20892-1026, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, N.I.H., Extramural
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