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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-9-27
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pubmed:abstractText |
We have previously reported evidence that variation at GABA(A) receptor genes is associated with susceptibility to bipolar disorder with schizophrenia-like psychotic features (Research Diagnostic Criteria (RDC) schizoaffective disorder, bipolar type) with gene-wide significance at GABRB1, GABRA4, GABRB3, GABRA5, and GABRR3. Here we provide suggestive evidence implicating a sixth member of the gene family, GABRR1 (gene-wide P?=?0.0058; experiment-wide corrected significance P?=?0.052).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1552-485X
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pubmed:author |
pubmed-author:CaesarSianS,
pubmed-author:CraddockNickN,
pubmed-author:FarmerAnneA,
pubmed-author:FerrierNicolN,
pubmed-author:FortyLizL,
pubmed-author:FraserChristineC,
pubmed-author:Gordon-SmithKatherineK,
pubmed-author:GreenElaine KEK,
pubmed-author:GrozevaDetelinaD,
pubmed-author:HamshereMarian LML,
pubmed-author:HolmansPeter APA,
pubmed-author:JonesIan RIR,
pubmed-author:JonesLisaL,
pubmed-author:McGuffinPeterP,
pubmed-author:MoskvinaValentinaV,
pubmed-author:O'DonovanMichael CMC,
pubmed-author:OwenMichael JMJ,
pubmed-author:RussellEllieE,
pubmed-author:St ClairDavidD,
pubmed-author:YoungAllan HAH
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pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
153B
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1347-9
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pubmed:meshHeading |
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pubmed:year |
2010
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pubmed:articleTitle |
Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.
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pubmed:affiliation |
Department of Psychological Medicine and Neurology, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom. greenek@cf.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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