Source:http://linkedlifedata.com/resource/pubmed/id/20578461
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2010-6-28
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| pubmed:abstractText |
The HIV and multi-drug resistant tuberculosis (MDR-TB) epidemics are closely linked. In Thailand as part of a sentinel surveillance system, we collected data prospectively about pulmonary TB cases treated in public clinics. A subset of HIV-infected TB patients identified through this system had additional data collected for a research study. We conducted multivariate analysis to identify factors associated with MDR-TB. Of 10,428 TB patients, 2,376 (23%) were HIV-infected; 145 (1%) had MDR-TB. Of the MDR-TB cases, 52 (37%) were HIV-infected. Independent risk factors for MDR-TB included age 18-29 years old, male sex, and previous TB treatment, but not HIV infection. Among new patients, having an injection drug use history was a risk factor for MDR-TB. Of 539 HIV-infected TB patients in the research study, MDR-TB was diagnosed in 19 (4%); the only significant risk factors were previous TB treatment and previous hepatitis. In Thailand, HIV is common among MDR-TB patients, but is not an independent risk factor for MDR-TB. Populations at high risk for HIV-young adults, men, injection drug users - should be prioritized for drug susceptibility testing.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0125-1562
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| pubmed:author |
pubmed-author:AkksilpSomsakS,
pubmed-author:AnuwatnonthakateAmornratA,
pubmed-author:BurapatChannawongC,
pubmed-author:KittikraisakWanitchayaW,
pubmed-author:MankatitthamWirojW,
pubmed-author:MonkongdeePatamaP,
pubmed-author:NateniyomSriprapaS,
pubmed-author:NgamlertKeeratayaK,
pubmed-author:RienthongSomsakS,
pubmed-author:SattayawuthipongWanchaiW,
pubmed-author:SirinakChawinC,
pubmed-author:SumnapunSurinS,
pubmed-author:TapperoJordan WJW,
pubmed-author:VarmaJay KJK,
pubmed-author:WattanaamornkiatWanpenW,
pubmed-author:WellsCharles DCD,
pubmed-author:YamadaNorioN
|
| pubmed:issnType |
Print
|
| pubmed:volume |
40
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1264-78
|
| pubmed:meshHeading |
pubmed-meshheading:20578461-Adolescent,
pubmed-meshheading:20578461-Adult,
pubmed-meshheading:20578461-Female,
pubmed-meshheading:20578461-HIV Infections,
pubmed-meshheading:20578461-Humans,
pubmed-meshheading:20578461-Logistic Models,
pubmed-meshheading:20578461-Male,
pubmed-meshheading:20578461-Middle Aged,
pubmed-meshheading:20578461-Multivariate Analysis,
pubmed-meshheading:20578461-Prospective Studies,
pubmed-meshheading:20578461-Risk Factors,
pubmed-meshheading:20578461-Sentinel Surveillance,
pubmed-meshheading:20578461-Substance Abuse, Intravenous,
pubmed-meshheading:20578461-Thailand,
pubmed-meshheading:20578461-Tuberculosis, Multidrug-Resistant,
pubmed-meshheading:20578461-Tuberculosis, Pulmonary
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Multi-drug resistant TB and HIV in Thailand: overlapping, but not independently associated risk factors.
|
| pubmed:affiliation |
Office of Disease Prevention and Control 7, Ubon Ratchathani, US Centers for Disease Control and Prevention Collaboration, Nonthaburi.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Corrected and Republished Article
|