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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2010-7-16
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pubmed:abstractText |
A direct and specific comparison of a trifluoromethyl group with the corresponding pentafluorosulfanyl group is made in terms of primary affinity and pharmacokinetic properties.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1464-3405
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4566-8
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pubmed:meshHeading |
pubmed-meshheading:20573506-Animals,
pubmed-meshheading:20573506-Azabicyclo Compounds,
pubmed-meshheading:20573506-Fluorine,
pubmed-meshheading:20573506-Heterocyclic Compounds, 2-Ring,
pubmed-meshheading:20573506-Humans,
pubmed-meshheading:20573506-Rats,
pubmed-meshheading:20573506-Receptors, Dopamine D3,
pubmed-meshheading:20573506-Sulfur,
pubmed-meshheading:20573506-Triazoles
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pubmed:year |
2010
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pubmed:articleTitle |
A specific and direct comparison of the trifluoromethyl and pentafluoro sulfanyl groups on the selective dopamine D(3) antagonist 3-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-1-phenyl-3-azabicyclo[3.1.0]hexane template.
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pubmed:affiliation |
Neurosciences Centre of Excellence, GlaxoSmithKline Medicines Research Centre, Verona, Italy. fm20244@gsk.com
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pubmed:publicationType |
Journal Article
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