Source:http://linkedlifedata.com/resource/pubmed/id/20562610
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2010-6-23
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| pubmed:abstractText |
The lower esophageal sphincter (LES) in patients with gastroesophageal reflux disease often has a low resting pressure and a short abdominal length. The mechanism by which this occurs is unknown. We hypothesize that gastric distension causes progressive effacement of the abdominal portion of the LES, exposing it to acid injury resulting in mucosal and sphincter damage. Our aim was to assess in normal subjects the effect of gastric distension on the LES length and pressure and its exposure to acid gastric juice.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
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| pubmed:issn |
1528-1140
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
252
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
57-62
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| pubmed:meshHeading |
pubmed-meshheading:20562610-Adult,
pubmed-meshheading:20562610-Esophageal Sphincter, Lower,
pubmed-meshheading:20562610-Female,
pubmed-meshheading:20562610-Gastric Acidity Determination,
pubmed-meshheading:20562610-Gastric Juice,
pubmed-meshheading:20562610-Humans,
pubmed-meshheading:20562610-Male,
pubmed-meshheading:20562610-Middle Aged,
pubmed-meshheading:20562610-Pressure,
pubmed-meshheading:20562610-Stomach
|
| pubmed:year |
2010
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| pubmed:articleTitle |
The impact of gastric distension on the lower esophageal sphincter and its exposure to acid gastric juice.
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| pubmed:affiliation |
Division of Thoracic and Foregut Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
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| pubmed:publicationType |
Journal Article
|