Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-7-30
pubmed:abstractText
Patients who have had prior reactions to iodinated contrast material have increased risk for repeat reactions. Nonionic contrast agents have been reported to reduce the risk of contrast reactions. A multicenter study was undertaken to determine the repeat reaction rate using iohexol. Two hundred ninety-one repeat reactors were included in the study, of whom one-third received premedication. Sixteen patients (5.5%) experienced repeat reactions; none was severe, and only one was more serious than the prior reaction. This is in contrast to the reported 16% to 44% repeated reaction rate for ionic agents. We conclude that iohexol is effective in reducing the occurrence of repeat reactions from the level observed with ionic agents without premedication. Iohexol appears to be as effective as ionic agents plus premedication in this high-risk group of patients.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0020-9996
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
The use of iohexol in patients with previous reactions to ionic contrast material. A multicenter clinical trial.
pubmed:affiliation
Department of Radiology, University of Texas Health Science Center, San Antonio 78284-7800.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't, Multicenter Study