Linked Life Data

20547733

Source:http://linkedlifedata.com/resource/pubmed/id/20547733

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-10-12
pubmed:abstractText
Mouse and human fibroblasts can be directly reprogrammed to pluripotency by the ectopic expression of four transcription factors (Oct3/4, Sox2, Klf4, and c-Myc) to yield induced pluripotent stem (iPS) cells. iPS cells can be generated even without the expression of c-Myc. The present study examined patterns of differentiation of mouse iPS cells into cardiomyocytes in three different cell lines reprogrammed by three or four factors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers, http://linkedlifedata.com/resource/pubmed/chemical/GKLF protein, http://linkedlifedata.com/resource/pubmed/chemical/Hdac5 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylases, http://linkedlifedata.com/resource/pubmed/chemical/Histones, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxamic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Kruppel-Like Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/Octamer Transcription Factor-3, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-myc, http://linkedlifedata.com/resource/pubmed/chemical/SOXB1 Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/trichostatin A
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1755-3245
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
314-23
pubmed:meshHeading
pubmed-meshheading:20547733-Acetylation, pubmed-meshheading:20547733-Animals, pubmed-meshheading:20547733-Biological Markers, pubmed-meshheading:20547733-Cell Differentiation, pubmed-meshheading:20547733-Cell Line, pubmed-meshheading:20547733-Cell Lineage, pubmed-meshheading:20547733-Cell Separation, pubmed-meshheading:20547733-Coculture Techniques, pubmed-meshheading:20547733-Embryonic Stem Cells, pubmed-meshheading:20547733-Flow Cytometry, pubmed-meshheading:20547733-Gene Expression Profiling, pubmed-meshheading:20547733-Gene Expression Regulation, Developmental, pubmed-meshheading:20547733-Histone Deacetylase Inhibitors, pubmed-meshheading:20547733-Histone Deacetylases, pubmed-meshheading:20547733-Histones, pubmed-meshheading:20547733-Hydroxamic Acids, pubmed-meshheading:20547733-Immunohistochemistry, pubmed-meshheading:20547733-Induced Pluripotent Stem Cells, pubmed-meshheading:20547733-Kruppel-Like Transcription Factors, pubmed-meshheading:20547733-Mice, pubmed-meshheading:20547733-Myocardial Contraction, pubmed-meshheading:20547733-Myocytes, Cardiac, pubmed-meshheading:20547733-Octamer Transcription Factor-3, pubmed-meshheading:20547733-Oligonucleotide Array Sequence Analysis, pubmed-meshheading:20547733-Proto-Oncogene Proteins c-myc, pubmed-meshheading:20547733-SOXB1 Transcription Factors, pubmed-meshheading:20547733-Time Factors, pubmed-meshheading:20547733-Transfection
pubmed:year
2010
pubmed:articleTitle
Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice.
pubmed:affiliation
Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan. koj@kuhp.kyoto-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't