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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-10-12
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pubmed:abstractText |
Cardiac resynchronization therapy (CRT) diminishes cardiac apoptosis and improves systolic function in heart failure (HF) patients with ventricular dyssynchrony. Plasma annexin A5 (AnxA5), a protein related to cellular damage, is associated with systolic dysfunction. We investigated whether the response to CRT is associated with plasma AnxA5. We also studied AnxA5 overexpression effects in HL-1 cardiomyocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1755-3245
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
304-13
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pubmed:meshHeading |
pubmed-meshheading:20542876-Adenosine Triphosphate,
pubmed-meshheading:20542876-Aged,
pubmed-meshheading:20542876-Animals,
pubmed-meshheading:20542876-Annexin A5,
pubmed-meshheading:20542876-Biological Markers,
pubmed-meshheading:20542876-Cardiac Resynchronization Therapy,
pubmed-meshheading:20542876-Case-Control Studies,
pubmed-meshheading:20542876-Caspase 3,
pubmed-meshheading:20542876-Cell Line,
pubmed-meshheading:20542876-Chi-Square Distribution,
pubmed-meshheading:20542876-Down-Regulation,
pubmed-meshheading:20542876-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20542876-Female,
pubmed-meshheading:20542876-Humans,
pubmed-meshheading:20542876-Linear Models,
pubmed-meshheading:20542876-Male,
pubmed-meshheading:20542876-Mice,
pubmed-meshheading:20542876-Middle Aged,
pubmed-meshheading:20542876-Mitochondria, Heart,
pubmed-meshheading:20542876-Myocytes, Cardiac,
pubmed-meshheading:20542876-Phosphorylation,
pubmed-meshheading:20542876-Protein Kinase C,
pubmed-meshheading:20542876-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20542876-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:20542876-Spain,
pubmed-meshheading:20542876-Stroke Volume,
pubmed-meshheading:20542876-Time Factors,
pubmed-meshheading:20542876-Transfection,
pubmed-meshheading:20542876-Treatment Outcome,
pubmed-meshheading:20542876-Ventricular Dysfunction, Left,
pubmed-meshheading:20542876-Ventricular Function, Left,
pubmed-meshheading:20542876-Ventricular Remodeling,
pubmed-meshheading:20542876-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2010
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pubmed:articleTitle |
Cardiac resynchronization therapy-induced left ventricular reverse remodelling is associated with reduced plasma annexin A5.
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pubmed:affiliation |
Division of Cardiovascular Sciences, Centre for Applied Medical Research, University of Navarra, Avda. Pío XII 55, 31008 Pamplona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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