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rdf:type |
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lifeskim:mentions |
umls-concept:C0001721,
umls-concept:C0026844,
umls-concept:C0038952,
umls-concept:C0040048,
umls-concept:C0205263,
umls-concept:C0596290,
umls-concept:C1135918,
umls-concept:C1171318,
umls-concept:C1704259,
umls-concept:C1704353,
umls-concept:C1705987
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pubmed:issue |
1
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pubmed:dateCreated |
2010-7-12
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pubmed:abstractText |
Vascular smooth muscle cells (SMCs) are exposed to fluid shear stress (FSS) after interventional procedures such as balloon-angioplasty. Whereas the effects of hemodynamic forces on endothelial cells are explored in detail, the influence of FSS on smooth muscle cell function is poorly characterized. Here, we investigated the effect of FSS on SMC gene expression and function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1097-6809
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
167-75
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pubmed:meshHeading |
pubmed-meshheading:20537494-Animals,
pubmed-meshheading:20537494-Apoptosis,
pubmed-meshheading:20537494-Carotid Artery Injuries,
pubmed-meshheading:20537494-Caspase 3,
pubmed-meshheading:20537494-Cell Proliferation,
pubmed-meshheading:20537494-Cell Survival,
pubmed-meshheading:20537494-Cells, Cultured,
pubmed-meshheading:20537494-DNA Replication,
pubmed-meshheading:20537494-Disease Models, Animal,
pubmed-meshheading:20537494-Gene Expression Profiling,
pubmed-meshheading:20537494-Glycoproteins,
pubmed-meshheading:20537494-Humans,
pubmed-meshheading:20537494-Immunohistochemistry,
pubmed-meshheading:20537494-Male,
pubmed-meshheading:20537494-Muscle, Smooth, Vascular,
pubmed-meshheading:20537494-Myocytes, Smooth Muscle,
pubmed-meshheading:20537494-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20537494-RNA, Messenger,
pubmed-meshheading:20537494-Rats,
pubmed-meshheading:20537494-Rats, Sprague-Dawley,
pubmed-meshheading:20537494-Recombinant Proteins,
pubmed-meshheading:20537494-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20537494-Stress, Mechanical,
pubmed-meshheading:20537494-Time Factors,
pubmed-meshheading:20537494-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival.
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pubmed:affiliation |
Section of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. johan.ekstrand@ki.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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