Source:http://linkedlifedata.com/resource/pubmed/id/20525960
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2010-8-20
|
| pubmed:abstractText |
Early detection of oral premalignant lesions (OPMLs) by visual inspection with toluidine blue has not been addressed. We conducted a community-based randomized controlled trial to assess whether using toluidine blue as an adjunctive tool for visual screening had a higher detection rate of OPMLs and could further reduce the incidence of oral cancer. In 2000, in Keelung, we randomly assigned a total of 7975 individuals, aged 15 years or older and with high-risk oral habits, to either the toluidine-blue-screened (TBS) group or the visual screening group. Results showed 5% more oral premalignant lesions and 79% more oral submucous fibrosis detected in the TBS group than in the control group. After a five-year follow-up ascertaining oral cancer development through linkage to the National Cancer Registry, the incidence rate in the TBS group (28.0 x 10(-5)) was non-significantly 21% lower than that in the control group (35.4 x 10(-5)).
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
D
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
1544-0591
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
89
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
933-7
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| pubmed:dateRevised |
2011-1-4
|
| pubmed:meshHeading |
pubmed-meshheading:20525960-Adolescent,
pubmed-meshheading:20525960-Adult,
pubmed-meshheading:20525960-Aged,
pubmed-meshheading:20525960-Aged, 80 and over,
pubmed-meshheading:20525960-Areca,
pubmed-meshheading:20525960-Chi-Square Distribution,
pubmed-meshheading:20525960-Coloring Agents,
pubmed-meshheading:20525960-Confidence Intervals,
pubmed-meshheading:20525960-Early Detection of Cancer,
pubmed-meshheading:20525960-Humans,
pubmed-meshheading:20525960-Leukoplakia, Oral,
pubmed-meshheading:20525960-Male,
pubmed-meshheading:20525960-Mass Screening,
pubmed-meshheading:20525960-Middle Aged,
pubmed-meshheading:20525960-Mouth Neoplasms,
pubmed-meshheading:20525960-Oral Submucous Fibrosis,
pubmed-meshheading:20525960-Precancerous Conditions,
pubmed-meshheading:20525960-Smoking,
pubmed-meshheading:20525960-Tolonium Chloride,
pubmed-meshheading:20525960-Young Adult
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
A community-based RCT for oral cancer screening with toluidine blue.
|
| pubmed:affiliation |
Division of Biostatistics, Graduate Institute of Epidemiology/Centre of Biostatistics Consultation, College of Public Health, National Taiwan University, Room 533, No. 17, Hsu-chow Road, Taipei, 100, Taiwan.
|
| pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
|