Source:http://linkedlifedata.com/resource/pubmed/id/20522999
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-6-4
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pubmed:abstractText |
A new nortriterpenoid, 20-hydroxymicrandilactone D (1) and a novel lignan glycoside, lancilignanside A (2) were isolated from leaves and stems of Schisandra lancifolia, together with three known nortriterpenoids (3-5) and nine known phenolics (6-14). The structures of new compounds 1 and 2 were determined by detailed analysis of their 1D and 2D NMR spectra, and chemical evidences. In addition, compounds 1-2, 6-7, and 9-11 showed anti-human immunodeficiency virus (HIV)-1 activities with 50% effective concentration (EC(50)) in the range of 3.0-99.0 microg/ml. Compound 12 was not bioactive in this assay with EC(50) more than 200 microg/ml.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1347-5223
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
852-5
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pubmed:dateRevised |
2011-3-8
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pubmed:meshHeading |
pubmed-meshheading:20522999-Anti-HIV Agents,
pubmed-meshheading:20522999-HIV-1,
pubmed-meshheading:20522999-Lignans,
pubmed-meshheading:20522999-Magnetic Resonance Spectroscopy,
pubmed-meshheading:20522999-Models, Molecular,
pubmed-meshheading:20522999-Plant Leaves,
pubmed-meshheading:20522999-Plant Stems,
pubmed-meshheading:20522999-Schisandra,
pubmed-meshheading:20522999-Triterpenes
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pubmed:year |
2010
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pubmed:articleTitle |
Chemical constituents from the leaves and stems of Schisandra lancifolia.
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pubmed:affiliation |
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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