Source:http://linkedlifedata.com/resource/pubmed/id/20516054
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2011-1-5
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| pubmed:abstractText |
Measurement of the diaphragm electromyogram (EMGdi) elicited by phrenic nerve stimulation could be useful to assess neonates suffering from respiratory distress due to diaphragm dysfunction, as observed in infants with abdominal wall defects (AWD) or congenital diaphragmatic hernia (CDH). The study aims were to assess the feasibility of recording EMGdi using a multipair oesophageal electrode catheter and examine whether diaphragm muscle and/or phrenic nerve function was compromised in AWD or CDH infants. Diaphragm compound muscle action potentials elicited by magnetic phrenic nerve stimulation were recorded from 18 infants with surgically repaired AWD (n = 13) or CDH (n = 5), median (range) gestational age 36.5 (34-40) weeks. Diaphragm strength was assessed as twitch transdiaphragmatic pressure (TwP(di)). One AWD patient had prolonged phrenic nerve latency (PNL) bilaterally (left 9.31 ms, right 9.49 ms) and two CDH patients had prolonged PNL on the affected side (10.1 ms and 10.08 ms). There was no difference in left and right TwP(di) in either group. PNL correlated significantly with TwP(di) in CDH (r = 0.8; p = 0.009). Oesophageal EMG and magnetic stimulation of the phrenic nerves can be useful to assess phrenic nerve function in infants. Reduced phrenic nerve conduction accompanies the reduced diaphragm force production observed in infants with CDH.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jan
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| pubmed:issn |
1399-3003
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
37
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
143-9
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| pubmed:meshHeading |
pubmed-meshheading:20516054-Abdominal Wall,
pubmed-meshheading:20516054-Diaphragm,
pubmed-meshheading:20516054-Electric Stimulation,
pubmed-meshheading:20516054-Electrodes,
pubmed-meshheading:20516054-Electromyography,
pubmed-meshheading:20516054-Esophagus,
pubmed-meshheading:20516054-Hernia, Diaphragmatic,
pubmed-meshheading:20516054-Humans,
pubmed-meshheading:20516054-Infant,
pubmed-meshheading:20516054-Infant, Newborn,
pubmed-meshheading:20516054-Magnetics,
pubmed-meshheading:20516054-Muscles,
pubmed-meshheading:20516054-Phrenic Nerve,
pubmed-meshheading:20516054-Pressure
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| pubmed:year |
2011
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| pubmed:articleTitle |
Diaphragm electromyogram in infants with abdominal wall defects and congenital diaphragmatic hernia.
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| pubmed:affiliation |
Division of Asthma, Allergy and Lung Biology, King's College, London, UK.
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| pubmed:publicationType |
Journal Article
|