Linked Life Data

20515273

Source:http://linkedlifedata.com/resource/pubmed/id/20515273

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-6-2
pubmed:abstractText
The standardisation of measurements of protein biomarkers, which are potentially heterogeneous in terms of fragmentation, modification, substitution, primary, secondary, tertiary and quaternary structure, is a demanding task. However, they are a prime target for standardisation efforts due to the importance of protein biomarkers in diagnostics and health care and the typically observed significant discrepancies in measurement results obtained with non-standardized platforms. Based on the experience gathered during successfully completed projects for the production of reference materials, pragmatic approaches are described how standardisation could become feasible despite the fuzziness of the target analytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0085-591X
pubmed:author
pubmed:issnType
Print
pubmed:volume
242
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
27-33
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Standardization of protein biomarker measurements: is it feasible?
pubmed:affiliation
European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel, Belgium. heinz.schimmel@ec.europa.eu
pubmed:publicationType
Journal Article