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rdf:type |
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lifeskim:mentions |
umls-concept:C0078058,
umls-concept:C0278678,
umls-concept:C0597298,
umls-concept:C0871261,
umls-concept:C1171892,
umls-concept:C1176020,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1749467,
umls-concept:C2698872,
umls-concept:C2911692
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-26
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pubmed:abstractText |
Angiogenesis is the target of several agents in the treatment of malignancies, including renal cell carcinoma (RCC). There is a real need for surrogate biomarkers that can predict selection of patients who may benefit from antiangiogenic therapies, prediction of disease outcome and which may improve the knowledge regarding mechanism of action of these treatments. Tyrosine kinase inhibitors (TKI) have proven efficacy in metastatic RCC (mRCC). However, the molecular mechanisms underlying the clinical response to these drugs remain unclear.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-10211101,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-10655437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-11846206,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-12778163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-12778165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-15534359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-15598929,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-16514137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-17215529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-17470880,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-17586751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-18041056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-18165647,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-18669461,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-18840822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-19284623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-19451442,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20502715-7518352
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AlloryYvesY,
pubmed-author:BastienLaurenceL,
pubmed-author:CalvoFabienF,
pubmed-author:CussenotOlivierO,
pubmed-author:DeslandesEmmanuelleE,
pubmed-author:MenashiSuzanneS,
pubmed-author:MourahSamiaS,
pubmed-author:NaïmiBenyoussefB,
pubmed-author:PauleBernardB,
pubmed-author:PodgorniakMarie-PierreMP,
pubmed-author:PorcherRaphaelR,
pubmed-author:de La TailleAlexandreA
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e10715
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20502715-Antineoplastic Agents,
pubmed-meshheading:20502715-Carcinoma, Renal Cell,
pubmed-meshheading:20502715-Female,
pubmed-meshheading:20502715-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20502715-Humans,
pubmed-meshheading:20502715-Immunohistochemistry,
pubmed-meshheading:20502715-Indoles,
pubmed-meshheading:20502715-Kaplan-Meier Estimate,
pubmed-meshheading:20502715-Kidney Neoplasms,
pubmed-meshheading:20502715-Male,
pubmed-meshheading:20502715-Neoplasm Metastasis,
pubmed-meshheading:20502715-Protein Isoforms,
pubmed-meshheading:20502715-Pyrroles,
pubmed-meshheading:20502715-RNA, Messenger,
pubmed-meshheading:20502715-Solubility,
pubmed-meshheading:20502715-Treatment Outcome,
pubmed-meshheading:20502715-Vascular Endothelial Growth Factor A
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pubmed:year |
2010
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pubmed:articleTitle |
Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas.
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pubmed:affiliation |
Inserm, UMRS 940, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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