rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-6-24
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pubmed:abstractText |
DNA-damage-inducible transcript 3 (DDIT3), a candidate tumor suppressor gene (TSG), has been found involved in the regulation of cellular growth and differentiation. The epigenetic changes of TSGs are recently recognized as an abnormal mechanism contributing to the development of chronic myeloid leukemia (CML). The aim of this study was to investigate the methylation status of DDIT3 gene in CML patients.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20492726-10233889,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1756-9966
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
54
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pubmed:meshHeading |
pubmed-meshheading:20492726-Adolescent,
pubmed-meshheading:20492726-Adult,
pubmed-meshheading:20492726-Aged,
pubmed-meshheading:20492726-Aged, 80 and over,
pubmed-meshheading:20492726-Base Sequence,
pubmed-meshheading:20492726-Blotting, Western,
pubmed-meshheading:20492726-DNA Methylation,
pubmed-meshheading:20492726-Female,
pubmed-meshheading:20492726-Fusion Proteins, bcr-abl,
pubmed-meshheading:20492726-Humans,
pubmed-meshheading:20492726-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:20492726-Male,
pubmed-meshheading:20492726-Middle Aged,
pubmed-meshheading:20492726-Molecular Sequence Data,
pubmed-meshheading:20492726-Prognosis,
pubmed-meshheading:20492726-Promoter Regions, Genetic,
pubmed-meshheading:20492726-RNA, Messenger,
pubmed-meshheading:20492726-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20492726-Transcription, Genetic,
pubmed-meshheading:20492726-Transcription Factor CHOP,
pubmed-meshheading:20492726-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Methylation status of DDIT3 gene in chronic myeloid leukemia.
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pubmed:affiliation |
Department of Hematology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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