rdf:type |
|
lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0003316,
umls-concept:C0018213,
umls-concept:C0020792,
umls-concept:C0036639,
umls-concept:C0037813,
umls-concept:C0043406,
umls-concept:C0071728,
umls-concept:C0336791,
umls-concept:C0597357,
umls-concept:C0680730,
umls-concept:C1140694,
umls-concept:C1148554,
umls-concept:C1167331
|
pubmed:issue |
8
|
pubmed:dateCreated |
2010-8-5
|
pubmed:abstractText |
In addition to genetic susceptibility, Yersinia enterocolitica (YE) infection played an important causative role in the pathogenesis of Graves' disease (GD) through molecular mimicry. However, the specific YE proteins and epitopes recognized by anti-TSH receptor (TSHR) autoantibodies (TRAb) have not been fully clarified, resulting in conflicting results from clinical research.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1945-7197
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
95
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4012-20
|
pubmed:meshHeading |
pubmed-meshheading:20484489-Adolescent,
pubmed-meshheading:20484489-Adult,
pubmed-meshheading:20484489-Aged,
pubmed-meshheading:20484489-Autoantibodies,
pubmed-meshheading:20484489-Blotting, Western,
pubmed-meshheading:20484489-Computational Biology,
pubmed-meshheading:20484489-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20484489-Epitopes,
pubmed-meshheading:20484489-Female,
pubmed-meshheading:20484489-Graves Disease,
pubmed-meshheading:20484489-Humans,
pubmed-meshheading:20484489-Immunoglobulins, Thyroid-Stimulating,
pubmed-meshheading:20484489-Male,
pubmed-meshheading:20484489-Mass Spectrometry,
pubmed-meshheading:20484489-Middle Aged,
pubmed-meshheading:20484489-Porins,
pubmed-meshheading:20484489-Receptors, Thyrotropin,
pubmed-meshheading:20484489-Yersinia Infections,
pubmed-meshheading:20484489-Yersinia enterocolitica
|
pubmed:year |
2010
|
pubmed:articleTitle |
Identification of outer membrane porin f protein of Yersinia enterocolitica recognized by antithyrotopin receptor antibodies in Graves' disease and determination of its epitope using mass spectrometry and bioinformatics tools.
|
pubmed:affiliation |
Division of Endocrinology and Metabolism, Provincial Hospital, Shandong University, 324 Jing Wu Road, Jinan 250021, China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|